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Diabetes Triggers

In short, anyone. Diabetes transcends age, gender, social status, caste or creed, job and race. Anyone can be susceptible to diabetes if they do not understand the risks associated with it.

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About Diabetes

Diabetes is a group of diseases characterized by high blood glucose levels that result from defects in the body's ability to produce and/or use insulin.

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Can I get Diabetes?

Anyone can get diabetes. Learn about the risks and symptoms of diabetes and how to avoid it.

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"Diabrisk-sl " : Evaluation of risk factors in the development of Type 2 diabetes and cardiovascular disease and correction through non pharmocological  Life Style Modification in Young Urban Sri Lankan Population

The study objective was aimed at reducing the burden of T2DM with a low cost primary prevention strategy.

It was a Randomised control parallel group clinical trial based on cluster sampling. 23,296 (5-40 yrs) healthy young (males 47%)  urban subjects were screened for 4 risk factors (RFs): ↑BMI, ↑Waist circumference (WC), ↓Physical Activity (PA), and family history (FH). Based on the first screening, subjects with ≥2Risk factors were 23%  (n = 5164) 4682 volunteered to be followed up with advice on Intensive-Life style modification [Study ] (3 monthly n= 2352) and Less Intensive –Life style modification  [Control ] (12 monthly  n= 2330).

Results:-

Baseline

  • 23% had 2 or more risk factors
  • Physical Inactivity 39%;>WC 31.7%; first degree family history 26.2%;>BMI 20.9%
  • Dysglycaemia <20yrs - 8.2%, [DM + pre-DM] >20yr - 22.1% and Overall- 15.3%

 Final results:

  • RELATIVE RISK REDUCTION [RRR] in new onset of  type 2 Diabetes 26%
  • RRR of IGT 18%
  • Primary endpoints 9% 
  • Regression from prediabetes to normoglycaemia 50%

Diabrisk-sl is a study carried out by the diabetes Association of Sri Lanka in collaboration with Metabolic Unit of  Kings College London -UK

This project was supported by a BRIDGES Grant from the International Diabetes Federation. BRIDGES, an International Diabetes Federation project, was supported by an educational grant from Lilly Diabetes and a grant awarded from the Diabetes Association of Sri Lanka.

 

 

 

Publications

  1. DIABRISK-SL Prevention of cardio-metabolic disease with lifestyle modification in young urban Sri Lankan's - study protocol for a randomized controlled trial (Wijesuriya et al. Trials 2011)
  2. High Prevalence of Cardio-Metabolic Risk Factors in a Young Urban Sri-Lankan Population (Wijesuriya et al. PLoS ONE 2012)

 

Here are a few interesting facts about diabetes and it’s penetration throughout the world.

  • There is NO CURE for diabetes
  • Adopting a healthy diet and increasing physical activity can reduce the development of Type 2 Diabetes by upto 80%
  • Type 2 diabetes is increasing in pandemic proportions in every country

Global

  • In 2014, 387 million people (8.3%) worldwide were affected by diabetes and 316 million people (6.9%) were affected by Impaired Glucose Tolerance (IGT). 
  • In 2035 the numbers are expected to rise to 592 million (10.1%) for diabetes and 471 million (8%) for IGT by 2035.
  • 77% of people with diabetes live in low- and middle-income countries
  • The greatest number of people with diabetes are between 40 and 59 years of age
  • 179 million people with diabetes are undiagnosed
  • Diabetes caused 5.1 million deaths in 2013; Every six seconds a person dies from diabetes
  • More than 79,000 children developed type 1 diabetes in 2013
  • More than 21 million live births were affected by diabetes during pregnancy in 2013
  • 50% or more of people with diabetes die of cardio vascular disease, heart and strokes.
  • 12.5 million people develop blindness each year due to diabetes
  • 1Diabetes is responsible for over 1 million amputations each year.
  • 120% of people with diabetes die of renal failure.
  • 1More than 2.5 million people worldwide are affected by diabetic retinopathy.

Regional 

  • In Africa, 5.1% or 22 million persons have diabetes while 76% of deaths due to diabetes are in people under the age of 60.
  • Europe has the highest prevalence of type 1 diabetes in children.
  • In the Middle East and North Africa, 1 in 10 adults has diabetes – 35 million.
  • More was spent on healthcare for diabetes in North America and the Caribbean than in any other region.
  • In South and Central America, the number of people with diabetes will increase by 60% by 2035.
  • In South-East Asia, 75 million persons live with diabetes while more than 50% of persons are unaware that they have diabetes. 
  • In the Western Pacific, 138 million adults have diabetes with the largest number 98.4 million from China.

National

Over 20 years;

  • 2010 - Rural 8.7% ; Urban 16.4% overall 10.3% = 2.1 million – Katulanda et al.
  • Dysglycaemia [ prediabetes and diabetes] 21.8% = 4.3 million – Katulanda et al.
  • 100 persons die of diabetes and heart disease daily – 30% of all cause deaths.

Diabrisk-SL: Urban young  under 5-40 yrs [ 2008-2013]

  • 23%  - 2 or more risk factors.
  • Risk factors identified :- Pysical inactivity 39%, > waist 31.7%, , Familly Histoty 26.2%, > BMI 20.9%
  • At baseline Dysglycaemia<20 yrs  - 8.2%; >20 yrs - 22.1% Overall -15.3%
  • Persons with 2 or more risk factors were followed up for 4 years with Intensive Lifestyle modification - results 
  • relative risk reduction [RRR] of new onset T2DM - 26%
  • RRR of newonset of IGT - 18%
  • > 50% regression from Prediabetes to normoglycaemia

News

Screening Packages

Standard Screening Package

Includes FBS / Lipid Profile / HbA1c / Serum creatinine /Urine Albumin/Urine Sugar / Urine albumin creatine ratio / ECG /Eye check including fundal photography / Neuropathy Assessment / Full physical assessment / Doctor’s Consultation

Executive Screening Package

Includes FBS / Lipid Profile / HbA1c / Liver Profile / Renal Profile / ECG / Eye check including fundal photography / Neuropathy Assessment / Full physical assessment / Doctor’s Consultation